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hfap complementary dna  (Thermo Fisher)


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    Structured Review

    Thermo Fisher hfap complementary dna
    a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in <t>hFAP-knock-in</t> (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.
    Hfap Complementary Dna, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hfap+complementary+dna/DNA/med_rxiv__2025__11__26__25341068-228-11-34
    Average 99 stars, based on 1 article reviews
    hfap complementary dna - by Bioz Stars, 2026-10
    99/100 stars

    Images

    1) Product Images from "A DDR2-targeted PET tracer images activated fibroblasts in early pulmonary fibrosis"

    Article Title: A DDR2-targeted PET tracer images activated fibroblasts in early pulmonary fibrosis

    Journal: medRxiv

    doi: 10.1101/2025.11.26.25341068

    a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in hFAP-knock-in (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.
    Figure Legend Snippet: a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in hFAP-knock-in (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.

    Techniques Used: Positron Emission Tomography-Computed Tomography, Knock-In, Imaging

    Related Articles

    Over Expression:

    Article Title: A DDR2-targeted PET tracer images activated fibroblasts in early pulmonary fibrosis
    Article Snippet: HEK293T cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM; Gibco) supplemented with 10% fetal bovine serum (FBS; Gibco) and 1% penicillin-streptomycin (Gibco) at 37°C in a humidified atmosphere containing 5% CO2. .. To generate stable overexpression models, lentiviral vectors carrying human DDR2 or hFAP complementary DNA (IGE Biotechnology, Guangzhou, China) were constructed and co-transfected with packaging plasmids psPAX2 and pMD2.G into 293T cells using Lipofectamine 3000 (Invitrogen). .. HEK293T cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM; Gibco) supplemented with 10% fetal bovine serum (FBS; Gibco) and 1% penicillin-streptomycin (Gibco) at 37°C in a humidified atmosphere containing 5% CO2.

    Construct:

    Article Title: A DDR2-targeted PET tracer images activated fibroblasts in early pulmonary fibrosis
    Article Snippet: HEK293T cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM; Gibco) supplemented with 10% fetal bovine serum (FBS; Gibco) and 1% penicillin-streptomycin (Gibco) at 37°C in a humidified atmosphere containing 5% CO2. .. To generate stable overexpression models, lentiviral vectors carrying human DDR2 or hFAP complementary DNA (IGE Biotechnology, Guangzhou, China) were constructed and co-transfected with packaging plasmids psPAX2 and pMD2.G into 293T cells using Lipofectamine 3000 (Invitrogen). .. HEK293T cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM; Gibco) supplemented with 10% fetal bovine serum (FBS; Gibco) and 1% penicillin-streptomycin (Gibco) at 37°C in a humidified atmosphere containing 5% CO2.



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    hfap complementary dna  (Thermo Fisher)
    99
    Thermo Fisher hfap complementary dna
    a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in <t>hFAP-knock-in</t> (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.
    Hfap Complementary Dna, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hfap+complementary+dna/DNA/med_rxiv__2025__11__26__25341068-228-11-34
    Average 99 stars, based on 1 article reviews
    hfap complementary dna - by Bioz Stars, 2026-10
    99/100 stars
    		  Buy from Supplier

    Image Search Results


    a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in hFAP-knock-in (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.

    Journal: medRxiv

    Article Title: A DDR2-targeted PET tracer images activated fibroblasts in early pulmonary fibrosis

    doi: 10.1101/2025.11.26.25341068

    Figure Lengend Snippet: a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in hFAP-knock-in (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.

    Article Snippet: To generate stable overexpression models, lentiviral vectors carrying human DDR2 or hFAP complementary DNA (IGE Biotechnology, Guangzhou, China) were constructed and co-transfected with packaging plasmids psPAX2 and pMD2.G into 293T cells using Lipofectamine 3000 (Invitrogen).

    Techniques: Positron Emission Tomography-Computed Tomography, Knock-In, Imaging